Contribution of electron microscopy to study in vitro inositol effects on human spermatozoa.
نویسندگان
چکیده
Infertility is a worldwide problem and male partner contributes to almost 30% of cases of infertility. The term oligoasthenoteratospermia is related to defective spermatogenesis and is characterized by a reduction of motility and number of spermatozoa and a change in their morphology. Electron microscopes are frequently used in order to evaluate sperm pathology and overall to establish a correlation between structural and functional deficiencies of altered sperm. High levels of reactive oxygen species endanger sperm function and viability. The correlation between male infertility, reactive oxygen species levels and the innovative therapeutic strategy employing inositol has been highlighted through analysis of literature data.
منابع مشابه
Inositol activity in oligoasthenoteratospermia--an in vitro study.
BACKGROUND Oligoasthenoteratospermia, a reduction in motilty and number of spermatozoa and a change in their morphology, is one of the most relevant causes of infertility in men. One of the factors, which may influence male infertility is linked to the production of reactive oxygen species (ROS) by morphologically altered spermatozoa. Spermatozoa are more susceptible than other cell species to ...
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ورودعنوان ژورنال:
- European review for medical and pharmacological sciences
دوره 21 2 Suppl شماره
صفحات -
تاریخ انتشار 2017